Exam Date: 8:00 AM Monday, Nov. 23
These instructional objectives provide you with a guide for learning the course material. I will provide a comprehensive forumla sheet with the exam. During the examination you should be able to:
Matlab
- Write the command(s) to define a variable as another variable, single number, range of numbers in Matlab.
- Performa calculations on lists of nubmers.
- Write the command(s) for calculating an equation in Matlab.
- Write the function plot(x,y) with proper variables for plotting data in Matlab.
Mass Balances
- Define system, system boundary, open system, closed system, control volume, half-life, rate constant, and lumped model.
- Determine the appropriate control volume for a system.
- Derive the mass balance equation for a system.
- Solve problems using a mass balance.
- Calculate the concentration, rate constant, or half-life of a tracer molecule or drug.
- List the three assumptions about a compartment.
- Explain when a single compartment model versus two-compartment model is appropriate in pharmacokinetics.
- Calculate the concentration of a drug over time in a single-compartment model given a single dose or multiple doses.
- Calculate the minimum, maximum, and average concentration of a drug in a single-compartment model.
- Calculate the concentration of a drug over time in a two-compartment model given a single dose or multiple doses.
Bioinstrumentation
- Given two of voltage, current, resistance, use Ohm’s law to find the third.
- Use Kirchhoff’s current law to analyze circuits.
- Use Kirchhoff’s voltage law to analyze circuits.
- Combine resistors in series and parallel.
- Calculate the change in resistance of a resistance temperature detector (RTD).
- Use the thermistor equation to calculate temperature, resistance, or \(\beta\).
- Calculate transmittance and absorbance.
- Use the Beer-Lambert law to find concentration, intensity, (molar extinction coefficient), or path length.
Bioinformatics
- Create a mathematical model of a single neuron (perceptron).
- Calculate output from a single neuron.
- Given a neuron, determine the equation for a line that separates two classes of inputs.
- Distinguish between linearly and non-linearly separable data.
- Describe how a neural network can classify non-linearly separable data.
Bioimaging
- Given two of wavelength, speed of light, and frequency, calculate the third.
- Calculate the energy or frequency associated with electromagnetic radiation, calculate the other.
- Calculate one of number of transmitted x-rays, number of incident x-rays, tissue linear attenuation, and tissue thickness, given all others.
- Calculate the half-layer value of tissue.
- Explain how x-rays can produce medical images.
- Explain how ultrasound can produce images.
- Calculate the time required for an ultrasound signal to travel through one or more tissues.
- Explain how ultrasound can estimate blood velocity.
- Given two of speed of sound in tissue, tissue thickness, and time, calculate the third.
- Calculate one of speed of sound in blood, frequency change, initial frequency of transmitted signal, velocity of blood flow, and transducer angle, given all others.
- Explain how a bitmapped image is represented inside a computer.
- Describe how an image filter works.
- Calculate spatial resolution from an image.
- Calculate a new pixel value given a kernel.
Statistics
- Define probability.
- Define true negative, true positive, false negative, false positive.
- Define prevalence, sensitivity, specificity, positive predictive value, negative predictive value.
- Use conditional probability to evaluate the odds a medical test is correct.
- Calculate the mean, variance, and standard deviation of data.
- Calculate the probability of an observation in a normal distribution.
- Calculate the percentile of an observation, or an observation given a percentile, in a normal distribution.
- Use hypothesis testing to compare two independent means.
Solidworks
- Explain the difference between extruded boss/base and extruded cut.
- Define fillet.
- Explain the difference between a load and a fixture.
- Explain what the colors mean when interpreting the stress results.
- Explain what shapes could be used to create a simple part.