Journal Articles

  1. Cummins, B., R. Chinthapatla, F. Ligler, G. Walker, “A Time-Dependent Model for Fluid Flow in Porous Materials with Multiple Pore Sizes,” Analytical Chemistry, 89(8), pp. 4377–4381, 2017. http://dx.doi.org/10.1021/acs.analchem.6b04717.
  2. Cummins, B., R. Chinthapatla, B. Lenin, F. Ligler, G. Walker, “Modular Pumps as Programmable Hydraulic Batteries for Microfluidic Devices,” Technology, 5(1), pp. 21–30, 2017. http://dx.doi.org/10.1142/S2339547817200011
  3. Pedersen, J., J. Shim, J. Macdonald, G. Walker, M. Andersen, H. Clewell, M. Yoon, “Fluid Dynamic Modeling to Support the Development of Flow-based Hepatocyte Culture Systems for Metabolism Studies,” Frontiers in Bioengineering and Biotechnology, 4, 2016.
  4. Murray, I., G. Walker, M. Bereman, “Improving the Analytical Performance and Versatility of Paper Spray Mass Spectrometry via Paper Microfluidics,” Analyst, 141, pp. 4065–4073, 2016.
  5. Permana, S., E. Grant, G. Walker, J. Yoder, “A Review of Automated Microinjection Systems for Single Cells in the Embryogenesis Stage,” IEEE/ASME Transactions on Mechatronics, 21(5), pp. 2391–2404, 2016.
  6. Cummins, B., F. Ligler, G. Walker, “Point-of-Care Diagnostics for Niche Applications,” Biotechnology Advances, 34, pp. 161–176, 2016.
  7. Ye, Y., J. Yu, C. Wang, N. Nguyen, J. Buse, G. Walker, Z. Gu, “Microneedle Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery,” Advanced Materials, 28(16), pp. 3115–3121, 2016.
    http://dx.doi.org/10.1002/adma.201506025
  8. Pacardo, D., B. Neupane, G. Wang, G.M. Walker, F.S. Ligler, “A Temperature Microsensor for Measuring Laser-Induced Heating in Gold Nanorods,” Analytical and Bioanalytical Chemistry, 407(3), pp. 719–725, 2015.
  9. Jiang, X., R.E. Jeffries, M.A. Acosta, A.P. Tikunov, J.M. Macdonald, G.M. Walker, M.P. Gamcsik, “Biocompatibility of Tygon Tubing in Microfluidic Cell Culture,” Biomedical Microdevices, 17(1), 2015. http://dx.doi.org/10.1007/s10544-015-9938-9
  10. Acosta, M., X. Jiang, P.K. Huang, C.S. Grant, G.M. Walker, and M.P. Gamcsik, “A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia,” Biomicrofluidics, 8, 054117, 2014. http://dx.doi.org/10.1063/1.4898788
  11. Vutha, A., B. Devaji, C. Lee, and G. Walker, “A Microfluidic Device for Thermal Particle Detection,” Microfluidics and Nanofluidics, 17(5), pp. 871–878, 2014.
  12. SooHoo, J., J. Herr, J.M. Ramsey, and G. Walker, “Microfluidic Cytometer for the Characterization of Cell Lysis,” Analytical Chemistry, 84(5), pp. 2195–2201, 2012.
  13. Dong, H. and G.M. Walker, “Adjustable-Stiffness Tubes via Thermal Modulation of a Low Melting Point Polymer,” Smart Materials and Structures, 21(4), pp. 042001, 2012.
  14. McPherson, A.L. and G.M. Walker, “A Photo-defined Membrane for Precisely Patterned Cellular and Microparticle Arrays,” AIP Advances, 2, pp. 012153, 2012.
  15. Dong, H. and G.M. Walker, “Adjustable Stiffness Films via Integrated Thermal Modulation,” Macromolecular Materials & Engineering, 295, pp. 735–741, 2010.
  16. McPherson, A.L. and G.M. Walker, “A Microfluidic Passive Pumping Coulter Counter,” Microfluidics and Nanofluidics, 9(4–5), pp. 897–904, 2010.
  17. O’Neill, A.T., N.A. Monteiro-Riviere, G.M. Walker, “Cell seeding curtains for high throughput proliferation assays,” Lab Chip, 9(12), pp. 1756–1762, 2009.
  18. SooHoo, J.R. and G.M. Walker, “Microfluidic Aqueous Two Phase Systems for Leukocyte Separation from Whole Blood,” Biomed Microdev, 11(2), pp. 323–329, 2009.
  19. O’Neill, A.T., N.A. Monteiro-Riviere, G.M. Walker, “Characterization of Microfluidic Human Epidermal Keratinocyte Culture,” Cytotechnology, 56, pp. 197–207, 2008.
  20. Sai, J., G. Walker, J. Wikswo, A. Richmond, “The IL sequence in the LLKIL motif in CXCR2 is required for full ligand induced activation of ERK, AKT and chemotaxis in HL60 cells,” J Biol Chem, 281(47), pp. 35931–41, 2007.
  21. Walker, G.M., N. Monteiro-Riviere, J. Rouse, A. T. O’Neill, “A Linear Dilution Microfluidic Device for Cytotoxicity Assays,” Lab Chip, 7(2), pp. 226–232, 2007.
  22. Walker, G.M., J. Sai, A. Richmond, M. Stremler, C.Y. Chung, J.P. Wikswo, “Effects of flow and diffusion on chemotaxis studies in a microfabricated gradient generator,” Lab Chip, 5(6), pp. 611–618, 2005.
  23. Rocheleau, J.V., G.M. Walker, W.S. Head, O.P. McGuinness, D.W. Piston, “Microfluidic glucose stimulation reveals limited pancreatic islet Ca2+i oscillations,” Proc Natl Acad Sci USA, 101(35), pp. 12899–12903, 2004.
  24. Walker, G.M., H.C. Zeringue, and D.J. Beebe, “Microenvironment design considerations for cellular scale studies,” Lab Chip, 4(2), pp. 91–97, 2004.
  25. Walker, G.M., M.S. Ozers, and D.J. Beebe, “Creation of virus gradients for cell infection within a microfluidic device,” Sens Act B, 98(2–3), pp. 347–355, 2004.
  26. Beebe, D.J., G.A. Mensing, and G.M. Walker, “Physics and Applications of Microfluidics in Biology,” Annu Rev Biomed Eng, 4, pp. 261–286, 2002 (invited).
  27. Walker, G.M., and D.J. Beebe, “A passive pumping method for microfluidic devices,” Lab Chip, 2(3), pp. 131–134, 2002.
  28. Walker, G.M., and D.J. Beebe, “An evaporation-based microfluidic sample concentration method,” Lab Chip, 2(2), pp. 57–61, 2002.
  29. Walker, G.M., M.S. Ozers, and D.J. Beebe, “Insect cell culture in microfluidic channels,” Biomed Microdev, 4(3), pp. 161–166, 2002 (invited).

Book Chapters

  1. Walker, G.M., “Microfluidic Aqueous Two-Phase Systems,” in D. Di Carlo, P. Tseng, and W. Lee (eds.), Microtechnology for Cell Manipulation and Sorting, New York, USA: Springer Science+Business Media, 2016.
  2. O’Neill, A.T. and G.M. Walker, “Linear Dilution Microfluidic Devices,” in K. Herold and A. Rasooly (eds.), Lab on a Chip Technologies and Applications, Norwich, UK: Caister Academic Press, 2009.
  3. Walker, G.M., “Microfluidics,” in J.G. Webster (ed.), Encyclopedia of Medical Devices and Instrumentation, Wiley, Hoboken, NJ, 2nd ed. 2006.
  4. Walker, G.M., “Minimally Invasive Surgical Robotics,” in J.G. Webster (ed.), Minimally Invasive Medical Technology, Bristol, UK: IOP Publishing, 2001.

Conference Papers/Abstracts

  1. Walker, G., S. Beach, M. Gamcsik, “Development of a Tumor-on-a-Chip for Hypoxia Studies,” In Vitro Biology Meeting 2017, June 10–14, Raleigh, NC, 2017.
  2. Chinthapatla, R., A. Young, S. Sivashankar, F. Ligler, M. Daniele, G. Walker, “Morphological Changes of HUVEC Under In Vitro Hemodynamic Conditions Using Modular Paper Pumps,” NCSU Undergraduate Research Symposium, April 12, Raleigh, NC, 2017.
  3. Beach, S., G. Walker, M. Gamcsik, “An Improved Microfluidic Device to Study Cancer Metastasis Under Hypoxia,” NCSU Undergraduate Research Symposium, April 12, Raleigh, NC, 2017.
  4. Murray, I., G. Walker, M. Bereman, “Implementing Paper Microfluidics with Paper Spray Mass Spectrometry for Improved Analytical Performance,” 64th ASMS Conference on Mass Spectrometry and Allied Topics, June 5–9, San Antonio, TX, 2016.
  5. Cummins, B.M., R. Chinthapatia, B. Lenin, F.S. Ligler, G.M. Walker, “Shaped Paper Pumps for Microfluidic Devices,” Europtrode XII - Conference on Optical Chemical Sensors and Biosensors, March 20–23, Graz, Austria, 2016.
  6. Ligler, F.S., B.M. Cummins, G.M. Walker, M. Lochhead, C. Hammett-Stabler, K. Caddell, J. Yeh, “Multiplexed Immunosensors for Niche Applications,” The International Chemical Congress of Pacific Basin Societies 2015, December 15–20, Honolulu, Hawaii, 2015.
  7. Caddell, K., B. Cummins, L. Kim, F. Ligler, G. Walker, J. Yeh, “Characterization of Intraoperative Parathyroid Hormone Sample Processing and Early Proof of Concept for a Point-of-Care Diagnostic Tool,” American Association of Endocrine Surgeons Annual Meeting, May 17–19, Nashville, TN, 2015.
  8. Ligler, F., B. Cummins, G.M. Walker, M. Lochhead, C. Hammett-Stabler, J. Yeh, K. Caddell, N. Hentz, “Point-of-Surgery Diagnostic for Parathyroid Hormone,” Pittcon Conference & Expo, March 8–12, New Orleans, LA, 2015.
  9. Cummins, B., N.G. Hentz, G.M. Walker, F.S. Ligler, “Point-of-surgery Diagnostic for Parathyroid Hormone,” Photonics West—SPIE BiOS, February 7–12, San Francisco, CA, 2015.
  10. Cummins, B., N.G. Hentz, G.M. Walker, F.S. Ligler, “Development Toward a Point-of-Surgery Test for Parathyroid Hormone,” Gordon Research Conference: Bioanalytical Sensors, June 22–27, 2014, Newport, RI, 2014.
  11. Acosta, M., X. Jiang, P.K. Huang, C.S. Grant, G.M. Walker, and M. Gamcsik, “Microfluidic Devices for Studying Intermittent Hypoxia Response in Cancer,” BMES Annual Fall Meeting, September 25–28, Seattle, WA, 2013.
  12. Jiang, X., M. Acosta, P.K. Huang, C.S. Grant, G.M. Walker, M. Gamcsik, “A Microfluidic Approach to Breast Cancer Metastasis Under Variable pO2 Levels,” BMES Annual Fall Meeting, September 25–28, Seattle, WA, 2013.
  13. Amatya, D., G. Walker, and R. Sachar, “Adjustable Stiffness Guide Catheter for Intracranial Intervention,” ASME Design of Medical Devices Conference, April 10–12, Minneapolis, MN, 2012.
  14. Kunduru, V. and G.M. Walker, “Integrated Microfluidic Devices for DNA Melting Curve Analysis,” First Annual Society for Laboratory Automation and Screening (SLAS) Conference, February 4–8, San Diego, CA, 2012.
  15. McPherson, A. and G.M. Walker, “Microfluidic Chip for Sub-Visible Particle Identification,” First Annual Society for Laboratory Automation and Screening (SLAS) Conference, February 4–8, San Diego, CA, 2012.
  16. Maltbie, C., I. Papautsky, S. van den Hoogenhof, D. Eddington, B. Gale, J.W. Choi, G. Walker, “Expanding the Introduction of Microfluidics through a Problem-Based Laboratory Course to Multiple Engineering Disciplines at Five Universities,” IEEE Frontiers in Education Conference, October 27–30, Arlington, VA, 2010.
  17. McPherson, A.L. and G.M. Walker, “A Microfluidic Passive Pumping Coulter Counter,” BMES Annual Fall Meeting, October 7–10, Pittsburgh, PA, 2009.
  18. McPherson, A.L. and G.M. Walker, “Low-cost microfluidic Coulter counter,” The Fifth International Conference on Microtechnologies in Medicine and Biology, April 1–3, Quebec City, Canada, pp. 154–155, 2009.
  19. Herr, J.K., J.P. Alarie, J. Soohoo, G.M. Walker, N. Sharpless, and J.M. Ramsey, “Integrated Microfluidic Cytometer for the Direct Analysis of Leukocytes in Whole Blood,” The Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences, October 12–16, San Diego, CA, pp. 1102–1104, 2008.
  20. Lee, C.H., G. Walker, A. O’Neill, and D.K. Manikkam, “Micro-Calorimeter with Enclosed Parylene Chambers for Bio/Chemical Applications,” The Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences, October 12–16, San Diego, CA, pp. 1429–1431, 2008.
  21. O’Neill, A., N. Monteiro-Riviere, and G. Walker, “Microfluidics-Based 96 Chamber Cell Culture System for Toxicology Studies,” BMES Annual Fall Meeting, October 1–4, St. Louis, MO, 2008.
  22. O’Neill, A.T., N.A. Monteiro-Riviere, and G.M. Walker, “Microfluidic HEK cultures as alternatives to mammalian models,” The Toxicologist CD-An official Journal of the Society of Toxicology, 102,S-1, 332, p.68, 2008.
  23. Peters, S., S.M. Gomez, G.M. Walker, and A.T. O’Neill, “Microfluidic Device for Controlled Reagent Delivery to Cell Culture,” 13th Annual Institute of Biological Engineering Conference}, March 6–9, Chapel Hill, NC, 2008.
  24. O’Neill, A. T., N.A. Monteiro-Riviere, and G.M. Walker, “Characterization of Human Epidermal Keratinocyte Cultures in Microfluidic Channels,” 13th Annual Institute of Biological Engineering Conference}, March 6–9, Chapel Hill, NC, 2008.
  25. McCullen, S.D., D.A. Young, J.R. Soo Hoo, G.M. Walker, and E.G. Loboa, “A Novel Microfluidic Platform for Application of Fluid Shear Stresses to Cells in 3D Culture,” 13th Annual Institute of Biological Engineering Conference}, March 6–9, Chapel Hill, NC, 2008.
  26. O’Neill, A., N.A. Monteiro-Riviere, and G.M. Walker, “High Throughput Microfluidic Cultures of Keratinocytes,” BMES Annual Fall Meeting, September 26–29, Los Angeles, CA, 2007.
  27. Soohoo, J. and G.M. Walker, “Microfluidic Liquid Filters for Leukocyte Isolation,” 29th Annual International Conference of the IEEE EMBS}, August 23–26, Lyon, France, pp. 6318–6321, 2007.
  28. Chandrasekaran, P., A. O’Neill, G. Walker, and D. Gerber, “Novel Microfluidic Device for Collagen Encapsulation of Hepatic Progenitor Cells,” 51st Biophysical Society Annual Meeting}, March 3–7, Baltimore, MD, 2007.
  29. Soo Hoo, J., N. Sharpless, and G. Walker, “Cell fractionalization of whole blood using aqueous two-phase separation in a microfluidic device,” BMES Annual Fall Meeting, October 11–14, Chicago, IL, 2006.
  30. O’Neill, A., N.A. Monteiro, and G. Walker, “A Serial Dilution Microfluidic Device for Nanomaterial Cytotoxicity Assays,” 28th Annual International Conference of the IEEE EMBS}, August 30–September 3, New York, NY, pp. 2836–2839, 2006.
  31. Hanson, A., J. Soo Hoo, G. Walker, and E. Loboa, “Novel microfluidic design for analyzing fluid shear stress induced viability and proliferation of human mesenchymal stem cells,” 2006 ASME Summer Bioengineering Conference, June 21–25, Amelia Island, FL, p. 31, 2006.
  32. O’Neill, A.T. and G.M. Walker, “A Serial Dilution Microfluidic Device for Cytotoxicity Screening,” BMES Annual Fall Meeting, September 28–October 1, Baltimore, MD, 2005.
  33. Hanson, A., G. Walker, R. Sumansinghe, M. Wall, E. Loboa, “Seeding of Human Mesenchymal Stem Cells onto Poly-L-Lactic Acid (PLLA) Scaffolds in a Flow Perfusion Microfluidic Chamber,” 2005 ASME Summer Bioengineering Conference, June 22–26, Vail, CO, p. 21, 2005.
  34. Walker, G.M., J. Sai, A. Richmond, J.P. Wikswo, “Flow effects on cell chemotaxis within a microfluidic device,” BMES Annual Fall Meeting, October 13–16, Philadelphia, PA, 2004.
  35. Rocheleau, J.V., G.M. Walker, W.S. Head, O.P. McGuinness, D.W. Piston, “Partial Pancreatic Islet Exposure to Glucose Causes Limited Coordination of Ca2+i Oscillations,” American Diabetes Association 64th Annual Scientific Sessions}, June 4–8, Orlando, FL, 2004.
  36. Rocheleau, J.V., G.M. Walker, W.S. Head, O.P. McGuinness, D.W. Piston, “Individual beta-cells of a pancreatic islet respond independently to their glucose environment,” Biophysical Society 48th Annual Meeting}, February 14?-18, Baltimore, MD, 2004.
  37. Walker, G.M., D.W. Piston, O.P. McGuinness, and J.V. Rocheleau, “A microfluidic device for partial surface treatment of islets of Langerhans,” The Seventh International Conference on Miniaturized Chemical and Biochemical Analysis Systems, October 5–9, Squaw Valley, CA, pp. 543–546, 2003.
  38. Walker, G.M., M.S. Ozers, and D.J. Beebe, “Microfluidic virus gradients for recombinant protein production optimization,” BMES Annual Fall Meeting, October 1–4, Nashville, TN, 2003.
  39. Bassett, J.I., G.M. Walker, and D.J. Beebe, “Mycological Culture in Microchannels,” The Second Joint Meeting of the IEEE EMBS and the BMES, October 23–26, Houston, TX, 2002.
  40. Walker, G.M., and D.J. Beebe, “Evaporation-driven microfluidic sample concentration,” The Second Annual International IEEE EMBS Special Topic Conference on Microtechnology in Medicine and Biology, May 2–4, Madison, WI, 2002.
  41. Walker, G.M., M.S. Ozers, and D.J. Beebe, “Growth Rates of Insect Cells in Microchannels,” Fifth International Conference on Miniaturized Chemical and Biochemical Analysis Systems, October 21–25, Monterey, CA, pp. 309–310, 2001.

Other

  1. Walker, G.M., “Microfluidics: Pensioning off pipettes,” Nature Chemistry, 3(6), pp. 428–429, 2011.