# BME 200 - Exam 2 Instructional Objectives

# Exam Date: Thursday, Dec 6, 8:00–11:20 AM in Brevard 122.

These instructional objectives provide you with a guide for learning the course material. During the examination you should be able to:

**Chapter 7**

- Define system, system boundaries, open system, closed system, homeostasis, steady state, half-life, internal and external respiration, alveolus, bronchi, trachea, spirometer, tidal volume.
- Determine the appropriate system boundaries for a system.
- Derive the mass balance equation for a system.
- Solve problems using a mass balance.
- Calculate the concentration of a molecule given its half-life and vice versa.
- Calculate the partial pressure of a gas.
- Calculate the concentration of a gas dissolved in a liquid.
- Calculate diffusive transport through a membrane.
- Use Fick’s law to calculate flux.

**Chapter 8**

- Use Newton’s law of viscosity to calculate shear stress, viscosity, or the shear rate \(dv/dx\).
- Use the Hagen-Poiseuille equation to calculate volumetric flow rate, pressure drop, or resistance of a vessel.
- Calculate the resistances of vessels in series and parallel.
- Use the equation \(\Delta P = QR\) to calculate pressure drop, volumetric flow rate, or vessel resistance.
- Calculate the hydrostatic pressure of a system.
- Calculate the Reynolds number of a system.
- Calculate the flux across the wall of a blood vessel.
- Explain the five steps of the cardiac cycle.
- Define diastole and systole.
- Identify right and left atria, right and left ventricles, AV valves, pulmonary valve, and aortic valve.
- Calculate compliance.
- Determine compliance from a graph.

**Chapter 10**

- Define stress, strain, Young’s modulus, elasticity, elastic material, viscoelastic material, Hooke’s law.
- Identify the main features of the stress-strain curve.
- Calculate deformation of materials given a force, and vice versa.
- Draw a free-body diagram of a system.
- Analyze the forces acting on a free-body diagram.
- Use LaPlace’s Law to calculate pressure.

**Chapter 11**

- Given two of voltage, current, resistance, use Ohm’s law to find the third.
- Use Kirchhoff’s current law to analyze circuits.
- Use Kirchhoff’s voltage law to analyze circuits.
- Calculate the resistivity of a material.
- Use the thermistor equation to calculate temperature, resistance, or \(\beta\).
- Calculate trasmittance.
- Calculate absorbance.
- Use the Beer-Lambert law to find concentration, intensity, \(\epsilon\) (molar extinction coefficient), or path length.

**Chapter 13**

- Develop and analyze simple pharmacokinetic models.
- Develop and analyze a simple model for cell growth rate.

**Chapter 15**

- List the three main three classes of biomaterials.
- Explain the characteristics of the main classes of biomaterials.
- Identify appropriate applications for each class of biomaterial.
- Define biocompatibility and biomaterial.
- Describe the two modes of failure.

**Statistics**

- Define probability.
- Define true negative, true positive, false negative, false positive.
- Define prevalence, sensitivity, specificity, positive predictive value, negative predictive value.
- Use conditional probability to evaluate the odds a medical test is correct.
- Calculate the mean, variance, and standard deviation of data.
- Calculate the probability of an observation in a normal distribution.
- Calculate the percentile of an observation, or an observation given a percentile, in a normal distribution.
- Calculate the confidence interval estimate of a mean when the standard deviation is known.

**Chapter 12**

- Given two of wavelength, speed of light, and frequency, calculate the third.
- Calculate the energy or frequency associated with electromagnetic radiation, calculate the other.
- Calculate one of number of transmitted x-rays, number of incident x-rays, tissue linear attenuation, and tissue thickness, given all others.
- Calculate the half-layer value of tissue.
- Explain how x-rays can produce medical images.
- Explain how ultrasound can produce images.
- Explain how ultrasound can estimate blood velocity.
- Given two of speed of sound in tissue, tissue thickness, and time, calculate the third.
- Calculate one of speed of sound in blood, frequency change, initial frequency of transmitted signal, velocity of blood flow, and transducer angle, given all others.
- Explain how a bitmapped image is represented inside a computer.
- Explain what a sharpening or smoothing filter does to an image.