BME 444: Biomedical Controls

Lectures: 11:00–12:15 TR, Zoom
Office: Zoom
Office hours: Check my calendar and email me,, for an appointment.

Course Objectives

By the end of the course, students will be able to:

  • Define signal and system
  • Describe control system characteristics
  • Model biomedical systems in the time and frequency domain
  • Determine the response of a biomedical system given an input
  • Analyze biomedical systems for stability
  • Design control systems given system specifications
  • Use MATLAB to solve control systems problems

General Information

If you have questions during reading, solving homework problems, writing up assignments, studying for exams, etc., send me an email with the question. I will respond to all students, “A student asked the following question…” so you will not be identified. Office visits are also welcome.


Homework is due at the beginning of class on the due date.

Homework is assigned to help you practice applying the principles you learn in class. Upload pictures/electronic copies of your HW to Blackboard.


Final Exam: Tuesday, April 27, 12:00–3:20 PM.


The final course grade comprises:

Homework 15%
Exams 50%
Final 35%

Final grades will be assigned based on the following scale:

Percentage Letter
>=93 A
92–90 A-
89–87 B+
86–83 B
82–80 B-
79–77 C+
76–73 C
72–70 C-
69–60 D
<60 F

Course Schedule

Lesson Date Topic HW Handouts
1 Jan 19 Intro to physical systems Notes
2 Jan 21 DEs of electrical systems Notes
3 Jan 26 DEs of mechanical systems Notes
4 Jan 28 DEs of mechanical systems cont’d HW1
Due Feb 4
5 Feb 02 DEs of fluid systems Notes
6 Feb 04 State Space HW2
Due Feb 11
7 Feb 09 State Space cont’d Notes
8 Feb 11 Numerical Simulation MATLAB HW3
Due Feb 18
MATLAB files
Feb 16 Snow Day
9 Feb 18 Transient analysis HW4
Due Feb 27
10 Feb 23 Transient analysis cont’d Notes
Markedup Notes
MATLAB files
Feb 25 Review Exam 1 IO
Mar 02 Exam 1
11 Mar 04 Frequency response HW5
Due Mar 11
12 Mar 09 Frequency response Notes
13 Mar 11 Physiological Systems Notes
14 Mar 16 Static Analysis MATLAB HW6
Due Mar 23
15 Mar 18 Lung model; Feedback Notes
Simulink file
16 Mar 23 Lung model; PID Notes
17 Mar 25 Block Diagrams; SS Error HW7
Due Apr 3
18 Mar 30 Stability Notes
Apr 01 Review Exam 2 IO
Apr 06 Exam 2
19 Apr 08 Example: Glucose Homeostasis 1 HW due Apr 13
GW Notes
20 Apr 13 Example: Glucose Homeostasis 2 HW due Apr 16
Normal model
21 Apr 15 Example: Glucose Controller HW due Apr 20
22 Apr 20 Example: Respirator PID Tuner HW due Apr 25
Apr 22 Review Final Exam IO

University of Mississippi Policies

Academic integrity

Students are expected to adhere to the guidelines for academic integrity outlined in the University of Mississippi Policy for Academic Conduct and Discipline. Cases of misconduct will be addressed according to the procedures outlined in the Policy. Your signature on any submitted work implies that you have neither given nor received unauthorized aid.

Student disabilities

Reasonable accommodations will be made for students with verifiable disabilities. In order to take advantage of available accommodations, students must register with the Office of Student Disability Services at 234 Martindale, 662-915-7128.


Students are expected to attend all classes. Read the Credits and Grades Policy (ACA.AR.200.003) and the Guidelines for Class Attendance Policies (ACA.AR.200.004) for more information. If you anticipate an excused absence on a due date, please notify me so that we can agree on an alternate due date.

Non-discrimination statement

The University of Mississippi provides equality of opportunity in education and employment for all students and employees. Accordingly, the University of Mississippi affirms its commitment to maintain a work environment for all employees and an academic environment for all students that is free from all forms of discrimination. Discrimination based on race, color, religion, creed, sex, national origin, age, disability, veteran status, or sexual orientation is a violation of state and federal law and/or University of Mississippi policy and will not be tolerated. Harassment of any person (either in the form of quid pro quo or creation of a hostile environment) based on race, color, religion, creed, sex, national origin, age, disability, veteran status, or sexual orientation also is a violation of state and federal law and/or University of Mississippi policy and will not be tolerated. Retaliation against any person who complains about discrimination is also prohibited. The University of Mississippi’s policies and regulations covering discrimination, harassment, and retaliation may be accessed here. Any person who feels that he or she has been the subject of prohibited discrimination, harassment, or retaliation should contact the Office of Equal Opportunity and Regulatory Compliance (EORC) or the Title IX Coordinator.