BME 444: Biomedical Controls

Lectures: 11:00–12:15 TX, Brevard 305
Office: Brevard A306
Office hours: Check my calendar and email me,, for an appointment.

Course Objectives

By the end of the course, students will be able to:

  • Define signal and system
  • Describe control system characteristics
  • Model biomedical systems in the time and frequency domain
  • Determine the response of a biomedical system given an input
  • Analyze biomedical systems for stability
  • Design control systems given system specifications
  • Use MATLAB to solve control systems problems

General Information

If you have questions during reading, solving homework problems, writing up assignments, studying for exams, etc., send me an email with the question. I will respond to all students, “A student asked the following question…” so you will not be identified. Office visits are also welcome.


Homework is due at the beginning of class on the due date.

Homework is assigned to help you practice applying the principles you learn in class. Upload pictures/electronic copies of your HW to Blackboard. Late homework will receive a maximum grade of 50%. After 24 hours, late HW will receive a grade of 0%.

IMPORTANT: You will lose points if I cannot read/follow your work. Make it neat, organized, and legible.


Final Exam: Tuesday, May 3, 12:00–3:20 PM.


The final course grade comprises:

Homework 15%
Exams 50%
Final 35%

Final grades will be assigned based on the following scale:

Percentage Letter
>=93 A
92–90 A-
89–87 B+
86–83 B
82–80 B-
79–77 C+
76–73 C
72–70 C-
69–60 D
<60 F

Course Schedule

Lesson Date Topic HW Handouts
1 Jan 18 Intro to physical systems Notes
2 Jan 20 DEs of electrical systems Notes
3 Jan 25 DEs of mechanical systems Notes
4 Jan 27 DEs of mechanical systems cont’d HW1
Due Feb 3
5 Feb 01 DEs of fluid systems
6 Feb 03 State Space
7 Feb 08 State Space cont’d
8 Feb 10 Numerical Simulation MATLAB
9 Feb 15 Transient analysis
10 Feb 17 Transient analysis cont’d
Feb 22 Review
Feb 24 Exam 1
11 Mar 01 Frequency response
12 Mar 03 Frequency response
13 Mar 08 Physiological Systems
14 Mar 10 Static Analysis MATLAB
Mar 15 Spring Break
Mar 17 Spring Break
15 Mar 22 Lung model; Feedback
16 Mar 24 Lung model; PID
17 Mar 29 Block Diagrams; SS Error
18 Mar 31 Stability
Apr 05 Review
Apr 07 Exam 2
19 Apr 12 Example: Glucose Homeostasis 1
20 Apr 14 Example: Glucose Homeostasis 2
21 Apr 19 Example: Glucose Controller
22 Apr 21 Example: Respirator PID Tuner
23 Apr 26 TBD
24 Apr 28 Review

University of Mississippi Policies


If you are sick, do not come to class. Get tested and send me an email. For details, consult

Academic integrity

Students are expected to adhere to the guidelines for academic integrity outlined in the University of Mississippi Policy for Academic Conduct and Discipline. Cases of misconduct will be addressed according to the procedures outlined in the Policy. Your signature on any submitted work implies that you have neither given nor received unauthorized aid.

Student disabilities

Reasonable accommodations will be made for students with verifiable disabilities. In order to take advantage of available accommodations, students must register with the Office of Student Disability Services at 234 Martindale, 662-915-7128.


Students are expected to attend all classes. Read the Credits and Grades Policy (ACA.AR.200.003) and the Guidelines for Class Attendance Policies (ACA.AR.200.004) for more information. If you anticipate an excused absence on a due date, please notify me so that we can agree on an alternate due date.

Non-discrimination statement

The University of Mississippi provides equality of opportunity in education and employment for all students and employees. Accordingly, the University of Mississippi affirms its commitment to maintain a work environment for all employees and an academic environment for all students that is free from all forms of discrimination. Discrimination based on race, color, religion, creed, sex, national origin, age, disability, veteran status, or sexual orientation is a violation of state and federal law and/or University of Mississippi policy and will not be tolerated. Harassment of any person (either in the form of quid pro quo or creation of a hostile environment) based on race, color, religion, creed, sex, national origin, age, disability, veteran status, or sexual orientation also is a violation of state and federal law and/or University of Mississippi policy and will not be tolerated. Retaliation against any person who complains about discrimination is also prohibited. The University of Mississippi’s policies and regulations covering discrimination, harassment, and retaliation may be accessed here. Any person who feels that he or she has been the subject of prohibited discrimination, harassment, or retaliation should contact the Office of Equal Opportunity and Regulatory Compliance (EORC) or the Title IX Coordinator.