BME 444 Biomedical Controls — Spring 2019
Lectures: 11:00–12:15 TR, Brevard Hall Room 122
Office: Glenn Walker, Brevard Hall Room 333, gmw@olemiss.edu
Office hours: Drop in or check my calendar and email me for an appointment.
Teaching Assistant: Jomiloju “JJ” Adebolu jjadebol@go.olemiss.edu
Required Text: Control Systems Engineering (7th Edition), Norman S. Nise, Wiley 2015.
Recommended Text: The Application of Control Theory to Physiological Systems, Howard T. Milhorn, Saunders 1966.
Course Objectives
By the end of the course, students will be able to:
 Define signal and system
 Describe control system characteristics
 Model biomedical systems in the time and frequency domain
 Determine the response of a biomedical system given an input
 Analyze biomedical systems for stability
 Design control systems given system specifications
 Use MATLAB to solve control systems problems
General Information
If you have questions during reading, solving homework problems, writing up reports, studying for exams, etc., send me an email with the question. I will respond to all students, “A student asked the following question…” so you will not be identified. Office visits are also welcome.
Homework
Homework is due at the beginning of class on the due date.
Homework is assigned to help you practice applying the principles you learn in class. If you are late to class, so is the homework. Late homework will receive a maximum grade of 50%. After 24 hours, late HW will receive a grade of 0%.
Exams
Final Exam: Tuesday, May 7, 12:00–3:20 PM in Brevard 122.
Bring your own calculator to the exams—cell phones will not be allowed as a substitute. Check your batteries before the exam. Exams missed with certified medical excuses or prior instructor approval will be dealt with individually.
Grades
The final course grade comprises:
Homework  20% 
Exams  45% 
Final  35% 
Final grades will be assigned based on the following scale:
Percentage  Letter 

>=93  A 
92–90  A 
89–87  B+ 
86–83  B 
82–80  B 
79–77  C+ 
76–73  C 
72–70  C 
69–67  D+ 
66–63  D 
62–60  D 
<60  F 
Course Schedule
Lesson  Date  Topic  HW  Handouts 

1  Jan 
Intro to technological systems (N 1)  HW1 
Slides 
2  Jan 
LaPlace; G(s); Electrical systems (N 2) 
Slides Matlab 

3  Jan 
G(s) of mechanical systems (N 2)  HW2 
Slides 
4  Jan 
G(s) of mechanical systems (N 2)  
5  Feb 
State space (N 3)  HW3 
State Space 
6  Feb 
State space (N 3)  Aquifer Problem  
7  Feb 
Intro to physiological systems (M 8)  HW4 Due Feb 21 
Physiological Systems 
8  Feb 
No class  
9  Feb 
Physiological system DE (M 3) 
Seat model  
10  Feb 
Time response (N 4)  HW5 Due Feb 28 
Slides 1st Order Response 
11  Feb 
Time response (N 4)  Slides  
12  Feb 
Review  IO Exam 1  
13  Mar 
Exam 1  
14  Mar 
Block diagrams (N 5)  
Mar 
Spring Break  
Mar 
Spring Break  
15  Mar 
Simplification; Signal flow (N 5)  HW6 Due Mar 26 

16  Mar 
Stability (N 6)  HW7 Due Mar 28 

17  Mar 
SS errors (N 7)  
18  Mar 
SS errors (N 7)  HW8 Due Apr 2 

19  Apr 
Root locus (N 8)  HW9 Due Apr 9 

20  Apr 
Frequency response (N 9)  
21  Apr 
Frequency response (N 9)  tf and zpk Stability Delay Worksheet 

22  Apr 
Frequency response (N 9)  HW10 Due Apr 16 
Nyquist Margins Worksheet 
23  Apr 
Review  IO Exam 2  
24  Apr 
Exam 2  
25  Apr 
Static characteristics (M 11)  
26  Apr 
Example: Breathing  
27  Apr 
Example: Glucose control  
28  May 
Example: Cardiovascular 
(N = Nise, M = Milhorn)
University of Mississippi Policies
Academic integrity
Students are expected to adhere to the guidelines for academic integrity outlined in the University of Mississippi Policy for Academic Conduct and Discipline. Cases of misconduct will be addressed according to the procedures outlined in the Policy. Your signature on any submitted work implies that you have neither given nor received unauthorized aid.
Student disabilities
Reasonable accommodations will be made for students with verifiable disabilities. In order to take advantage of available accommodations, students must register with the Office of Student Disability Services at 234 Martindale, 6629157128.
Attendance
Students are expected to attend all classes. Read the Credits and Grades Policy (ACA.AR.200.003) and the Guidelines for Class Attendance Policies (ACA.AR.200.004) for more information. If you anticipate an excused absence on a due date, please notify me so that we can agree on an alternate due date.
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